As obesity is a well-known risk factor for diseases like diabetes, heart diseases and for some cancers. Why not all obese suffer from all these diseases? Should all obese people lose weight?
Why are they “metabolically healthy”?
It is explained on the basis of Inflammation. It means your immune system has sensed a threat and is mobilizing to respond to it.
Chronic or systemic inflammation is when the “protect me” signal misfires. “Essentially, white blood cells inappropriately move into tissues, causing destruction,” explains Floyd Chilton, Ph.D., director of the NIH-sponsored Center for Botanical Lipids and Inflammatory Disease Prevention at Wake Forest Baptist Health School of Medicine in North Carolina. This reaction can happen anywhere in your body. “If it happens in the heart, you wind up with heart disease; if in the joint, it’s arthritis; in the brain, it might be dementia,” Chilton says.
The new research, published in the Journal of Clinical Endocrinology & Metabolism, is based on data from 2,040 people between the ages of 50 and 69 who were part of the Cork and Kerry Diabetes and Heart Disease Study, Phase II., between 2010 and 2011. All the study participants were interviewed about their lifestyle habits. They also underwent testing on their body mass indexes, inflammatory markers, and metabolic profiles.Researchers found an association between inflammatory markers and metabolic health of the study participants only, no matter their weight. The low levels of white blood cells and acute-phase response proteins (which grow in number during inflammation) indicates the metabolically healthy condition , as well as higher levels of the anti-inflammatory hormone adiponectin.